HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-(3-oxocyclopentyl)acetate → HCID 57516115, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-(3-oxocyclopentyl)acetate | HCID 11355614 | — |
| Reactant | (S)-2-amino-6-(5-amino-2-fluoro-phenyl)-3,5,5,6-tetramethyl-5,6-dihydro-3H-pyrimidin-4-one | HCID 57497157 | — |
| Reactant | HCID 178419135 | HCID 178419135 | — |
| Product | HCID 57516115 | HCID 57516115 | — |
Reaction Steps
The reductive amination of (S)-2-amino-6-(5-amino-2-fluoro-phenyl)-3,5,5,6-tetramethyl-5,6-dihydro-3H-pyrimidin-4-one (intermediate J) and (3-oxo-cyclopentyl)-acetic acid methyl ester using decaborane yielded a mixture of isomers of the title compound as a white foam. MS (ESI): m/z=419.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08815881B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-a8a2bb4bc5784bb180245fb32ea1f5f2 |
| Source note | uspto-grants-2014_08 |