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HRID2409197

反应详情

EQUATION

反应方程式

HRID 2409197 的结构方程式

REACTANTS

反应物

2
结构：C[C@](O)(C(=O)O)C(F)(F)F
HCID7019028

(2S)-3,3,3-Trifluoro-2-hydroxy-2-methylpropanoic acid

C4H5F3O3

结构：CN1C(=O)C(C)(C)[C@@](C)(c2cc(N)ccc2F)N=C1NC(=O)OC(C)(C)C
HCID57496584

未命名化合物

2 次

PRODUCTS

生成物

1
结构：CN1C(=O)C(C)(C)[C@@](C)(c2cc(NC(=O)[C@](C)(O)C(F)(F)F)ccc2F)N=C1N
HCID57516114

未命名化合物

PROCEDURE

实验过程

The coupling of [(S)-4-(5-amino-2-fluoro-phenyl)-1,4,5,5-tetramethyl-6-oxo-1,4,5,6-tetrahydro-pyrimidin-2-yl]-carbamic acid tert-butyl ester (intermediate F2) and (S)-3,3,3-trifluoro-2-hydroxy-2-methyl-propionic acid followed by deprotection of the intermediate yielded the title compound as a white solid. MS (ESI): m/z=419.2 [M+H]+.