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HRID2409200

反应详情

EQUATION

反应方程式

HRID 2409200 的结构方程式

REACTANTS

反应物

2
结构：Cc1cc(N)ccc1C#N
HCID8167081

4-amino-2-methylbenzonitrile

C8H8N2

结构：COc1ccc(C(NC2=N[C@](C)(c3cc(Br)ccc3F)C(C)(C)C(=O)N2C)(c2ccccc2)c2ccc(OC)cc2)cc1
HCID57497159

未命名化合物

2 次

PRODUCTS

生成物

1
结构：Cc1cc(Nc2ccc(F)c([C@@]3(C)N=C(N)N(C)C(=O)C3(C)C)c2)ccc1C#N
HCID66727840

未命名化合物

PROCEDURE

实验过程

The coupling of (S)-2-{[bis-(4-methoxy-phenyl)-phenyl-methyl]-amino}-6-(5-bromo-2-fluoro-phenyl)-3,5,5,6-tetramethyl-5,6-dihydro-3H-pyrimidin-4-one (intermediate K) and 4-amino-2-methyl-benzonitrile according to procedure B followed by deprotection yielded the title compound as a white solid. MS (ESI): m/z=394.1 [M+H]+.