HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2R,6S)-2,6-dimethyloxan-4-one → HCID 57497001, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2R,6S)-2,6-dimethyloxan-4-one | HCID 10441716 | — |
| Reactant | (S)-2-amino-6-(5-amino-2-fluoro-phenyl)-3,5,5,6-tetramethyl-5,6-dihydro-3H-pyrimidin-4-one | HCID 57497157 | — |
| Reactant | HCID 178419135 | HCID 178419135 | — |
| Product | HCID 57497001 | HCID 57497001 | — |
Reaction Steps
The reductive amination of (S)-2-amino-6-(5-amino-2-fluoro-phenyl)-3,5,5,6-tetramethyl-5,6-dihydro-3H-pyrimidin-4-one (intermediate J) and (2R,6S)-2,6-dimethyl-tetrahydro-pyran-4-one using decaborane yielded the title compound as a white solid. MS (ESI): m/z=391.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08815881B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-2ce7c66b0c4f4e55a876cfe5c3864baa |
| Source note | uspto-grants-2014_08 |