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HRID2409207

反应详情

EQUATION

反应方程式

HRID 2409207 的结构方程式

REACTANTS

反应物

2
结构：Nc1cccc2c1OCC2
HCID12805950

2,3-Dihydro-1-benzofuran-7-amine

C8H9NO

结构：COc1ccc(C(NC2=N[C@](C)(c3cc(Br)ccc3F)C(C)(C)C(=O)N2C)(c2ccccc2)c2ccc(OC)cc2)cc1
HCID57497159

未命名化合物

2 次

PRODUCTS

生成物

1
结构：CN1C(=O)C(C)(C)[C@@](C)(c2cc(Nc3cccc4c3OCC4)ccc2F)N=C1N
HCID57497038

未命名化合物

PROCEDURE

实验过程

The coupling of (S)-2-{[bis-(4-methoxy-phenyl)-phenyl-methyl]-amino}-6-(5-bromo-2-fluoro-phenyl)-3,5,5,6-tetramethyl-5,6-dihydro-3H-pyrimidin-4-one (intermediate K) and 2,3-dihydro-benzofuran-7-ylamine according to procedure B followed by deprotection yielded the title compound as an off-white solid. MS (ESI): m/z=397.2 [M+H]+.