4-(4-Fluorophenyl)piperidine → HCID 71178942, compound

Participants

Reaction Steps

Using ethyl 3-(N-tert-butylsulfamoyl)-7-(2-chloro-4-methylphenylamino)pyrazolo[1,5-a]pyrimidine-6-carboxylate (11.17 g, 24.0 mmol) obtained in step 3 and 4-(4-fluorophenyl)piperidine (5.93 g, 33.09 mmol) instead of 4-phenylpiperidine, and in the same manner as in Example 1 step 4, the title compound (8.33 g, 63%) was obtained.

Provenance & Evidence