4-(4-Fluorophenyl)piperidine → HCID 71179009, compound

Participants

Reaction Steps

Using ethyl 3-(N-tert-butylsulfamoyl)-7-(2-chloro-4-fluorophenylamino)pyrazolo[1,5-a]pyrimidine-6-carboxylate (4.98 g, 10.60 mmol) obtained in step 3 and 4-(4-fluorophenyl)piperidine (1.43 g, 7.97 mmol) instead of 4-phenylpiperidine, and in the same manner as in Example 1 step 4, the title compound (2.95 g, 93%) was obtained.

Provenance & Evidence