4-(4-Fluorophenyl)piperidine → HCID 71178976, compound

Participants

Reaction Steps

Using ethyl 3-(N-tert-butylsulfamoyl)-7-(2-chloro-5-fluorophenylamino)pyrazolo[1,5-a]pyrimidine-6-carboxylate (4.16 g, 8.85 mmol) obtained in step 3 and 4-(4-fluorophenyl)piperidine (2.04 g, 11.4 mmol) instead of 4-phenylpiperidine, and in the same manner as in Example 1 step 4, the title compound (3.54 g, 77%) was obtained.

Provenance & Evidence