Isocyanatocyclopropane → HCID 53377814, compound

Participants

Reaction Steps

Using 7-(2-fluoro-5-methylphenylamino)-6-[4-(4-fluorophenyl)piperidine-1-carbonyl]pyrazolo[1,5-a]pyrimidine-3-sulfonamide (0.10 g, 0.19 mmol) obtained in Example 31 step 5 and cyclopropylisocyanate (0.048 g, 0.57 mmol) instead of ethylisocyanate, and in the same manner as in Example 7, the title compound (0.053 g, 62%) was obtained.

Provenance & Evidence