4-(4-Fluorophenyl)piperidine → HCID 71179003, compound

Participants

Reaction Steps

Using ethyl 3-(N-tert-butylsulfamoyl)-7-(5-chloro-2-fluorophenylamino)pyrazolo[1,5-a]pyrimidine-6-carboxylate (1.82 g, 3.87 mmol) obtained in step 3 and 4-(4-fluorophenyl)piperidine (0.88 g, 4.89 mmol) instead of 4-phenylpiperidine, and in the same manner as in Example 1 step 4, the title compound (0.92 g, 47%) was obtained.

Provenance & Evidence