4-(4-Fluorophenyl)piperidine → HCID 71178935, compound

Participants

Reaction Steps

Using ethyl 3-(N-tert-butylsulfamoyl)-7-(2,5-difluorophenylamino)pyrazolo[1,5-a]pyrimidine-6-carboxylate (1.38 g, 3.04 mmol) obtained in step 3 and 4-(4-fluorophenyl)piperidine (0.70 g, 3.88 mmol) instead of 4-phenylpiperidine, and in the same manner as in Example 1 step 4, the title compound (0.64 g, 43%) was obtained.

Provenance & Evidence