1,4-Dioxane hydrochloride → HCID 67380985, compound

Participants

Reaction Steps

The compound (28 mg, 0.08 mmol) prepared in step 6 was dissolved in ethanol/1,4-dioxane, added with 3.7 N hydrochloric acid 1,4-dioxane solution. The resulting mixture was stirred overnight at room temperature. Once the reaction was completed, the mixture was concentrated under reduced pressure and washed with ethyl acetate. The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure to obtain the title compound (27 mg, yield: 79%, yellow solid).

Provenance & Evidence