Triacetoxyperiodinane → HCID 58424903, compound

Participants

Reaction Steps

The compound (50 mg, 0.18 mmol) prepared in step 4 was dissolved in dichloromethane (10 ml), added with Dess-Martin periodinane (112 mg, 0.26 mmol) at 0° C. The resulting mixture was stirred for 90 minutes at room temperature and poured into saturated sodium bicarbonate aqueous solution. The mixture was extracted with dichloromethane and washed with brine. The organic layer was dried over anhydrous sodium sulfate and concentrated to dryness. The residue was then purified by flash column chromatography (ethylacetate:hexane=1:1) to obtain the title compound (25 mg, yield: 50%, white solid).

Provenance & Evidence