Ethyl 3-(4-nitrophenyl)-2-propenoate → Ethyl 3-(4-aminophenyl)propanoate

Participants

Reaction Steps

Ethyl 3-(4-nitrophenyl)acrylate (3 g, 13.56 mmol) was dissolved in methanol/tetrahydrofuran (20 ml), added with 10%-palladium (Pd) (300 mg). The resulting mixture was stirred for one day under hydrogen gas at room temperature and filtered using celite to remove 10%-palladium (Pd). The filtrate was then concentrated under reduced pressure. The residue was then purified by flash column chromatography (hexane:ethylacetate=3:1) to obtain the title compound (2.14 g, yield: 82%, colorless liquid).

Provenance & Evidence