HCID 86657390, compound → HCID 58424856, compound

Participants

Reaction Steps

The compound (780 mg, 2.50 mmol) prepared in step 5 was dissolved in tetrahydrofuran, added dropwise with 2 M borane dimethyl sulfide tetrahydrofuran solution (6.24 ml, 12.49 mmol). The resulting mixture was stirred for 3 hours at room temperature and extracted with chloroform. The organic layer was dried over anhydrous magnesium sulfate and concentrated to dryness. The residue was then purified by flash column chromatography (chloroform:methanol=15:1) to obtain title compound (45 mg, yield: 75%, white solid).

Provenance & Evidence