HCID 58424856, compound → HCID 58424889, compound

Participants

Reaction Steps

The compound (200 mg, 0.67 mmol) prepared in step 6 was dissolved in dichloromethane, added with pyridinium chlorochromate (289 mg, 1.34 mmol) and silica gel (289 mg) at room temperature. The resulting mixture was stirred for 2 hours at room temperature and filtered to remove silica gel. The filtrate was extracted with dichloromethane, dried over anhydrous magnesium sulfate and concentrated to dryness. The residue was then purified by flash column chromatography (chloroform:methanol=15:1) to obtain the title compound (151 mg, yield: 76%, white solid).

Provenance & Evidence