HCID 58424979, compound → HCID 58424852, compound

Participants

Reaction Steps

The compound (650 mg, 2.29 mmol) prepared in step 4 was dissolved in ethanol (10 ml)/dichloromethane (10 ml) and added with 10%-palladium (Pd) (200 mg) at room temperature. The resulting mixture was stirred for one day under hydrogen gas and 10%-palladium was removed by using celite-filter. The filtrate was concentrated under reduced pressure and the residue was purified by flash column chromatography (chloroform:methanol=30:1) to obtain the title compound (320 mg, yield: 49%, white solid).

Provenance & Evidence