Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | Boron tribromide | HCID 25134 | — |
| Reactant | 1-Bromo-2-(3-methoxyphenyl)ethane | HCID 137450 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-(2-Bromoethyl)phenol | HCID 572300 | — |
Reaction Steps
A solution of 1-(2-bromoethyl)-3-methoxybenzene (1.00 g, 4.7 mmol) in CHCl3 (50 mL, 0.6 mol) was cooled to at 0° C. 1.0 M of BBr3 in DCM (27.9 mL) was cooled to 0° C. and added to the solution. The solution was allowed to warm to 30° C. over 30 minutes, then was poured into a solution of ice and 30% NH4OH, which was stirred at 0° C. for 30 minutes. The organic layer was taken and concentrated with no reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08815907B2 |
|---|
| Source dataset | uspto-grants-2014_08 |
|---|
| ORD ID | ord-d45fbf9652f9464e8c9da7254f55c123 |
|---|
| Source note | uspto-grants-2014_08 |
|---|
