HCID 178512921, compound → HCID 178418600, compound
Reaction equation
[OH-].[K+].[NH2:3][C@H:4]([C:12]([OH:14])=[O:13])[CH2:5][CH2:6][CH2:7][NH:8][C:9](=[NH:11])[NH2:10]>C(O)C>[NH2:3][C@H:4]([C:12]([OH:14])=[O:13])[CH2:5][CH2:6][CH2:7][NH:8][C:9](=[NH:10])[NH2:11]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 50 °C
Procedure
20 mg of Compound 1 in 100 μl of ethanol was added to one molar equivalent of L-arginine potassium hydroxide and then heated to 50° C. for approximately 10-12 hours to assist with the dissolution of the base. The L-arginine salt of Compound 1 was isolated by filtration under vacuum.
Workup
- dissolutionto assist with the dissolution of the base
Sources & evidence
- ORD record
- ord-b2d5ad6125bf4839a90098d87f567ad6
- Source dataset
- uspto-grants-2014_08
- Patent number
- US08815917B2
Reaction notes
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