4-[2-(Dimethylamino)ethoxy]aniline → 8-(2-Chloro-5-methoxy-phenyl)-quinoxaline-5-carboxylic acid [4-(2-dimethylamino-ethoxy)-phenyl]-amide

Participants

Role	Name	HCID	Charge
Reactant	4-[2-(Dimethylamino)ethoxy]aniline	HCID 6484655	—
Reactant	8-(2-Chloro-5-methoxy-phenyl)-quinoxaline-5-carboxylic acid [3-(4-ethyl-piperazin-1-yl)-phenyl]-amide	HCID 44515980	—
Product	8-(2-Chloro-5-methoxy-phenyl)-quinoxaline-5-carboxylic acid [4-(2-dimethylamino-ethoxy)-phenyl]-amide	HCID 59292826	—

Reaction Steps

The title compound was prepared in analogy to the procedure described in Step 14.1 but using 4-(2-dimethylamino-ethoxy)-phenylamine (Step 5.1) and 8-(2-chloro-5-methoxy-phenyl)-quinoxaline-5-carboxylic acid (Example 63). Title compound: ESI-MS: 476.9 [M]+; tR=3.43 min (System 3).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08815901B2
Source dataset	uspto-grants-2014_08
ORD ID	ord-9ca53890b1434e51ab86431a2b55428f
Source note	uspto-grants-2014_08