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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 2409657Erstellt: 25. Oktober 2026

6-(4-Methylpiperazin-1-yl)pyridin-3-amine → 8-(4-Methyl-thiophen-3-yl)-quinoxaline-5-carboxylic acid [6-(4-methyl-piperazin-1-yl)-pyridin-3-yl]-amide

https://huagongshe.com/reaction/2409657

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt6-(4-Methylpiperazin-1-yl)pyridin-3-amineHCID 2763390—
Edukt8-(4-Methylthiophen-3-yl)-quinoxaline-5-carboxylic acidHCID 66914550—
Produkt8-(4-Methyl-thiophen-3-yl)-quinoxaline-5-carboxylic acid [6-(4-methyl-piperazin-1-yl)-pyridin-3-yl]-amideHCID 44516283—

Reaktionsschritte

The title compound was prepared in analogy to the procedure described in Step 14.1 but stirring the reaction mixture for 20 h at rt, using 6-(4-methylpiperazin-1-yl)-pyridin-3-ylamine (prepared as described in Example 33 but using N-methyl-piperazine in Step 33.2) and 8-(4-methyl-thiophen-3-yl)-quinoxaline-5-carboxylic acid (Example 67). Title compound: ESI-MS: 445.0 [M+H]+; tR=3.42 min (System 1).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08815901B2
Quelldatensatzuspto-grants-2014_08
ORD IDord-f97b1dfb12c24c9f8b12038214d1c4f2
Quellennotizuspto-grants-2014_08