HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluoro-4-iodoaniline → 2,3-difluoro-N-(2-fluoro-4-iodophenyl)-5-(2-methoxyethoxy)-6-nitroaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluoro-4-iodoaniline | HCID 185694 | — |
| Reactant | 1,2,3-Trifluoro-5-(2-methoxyethoxy)-4-nitrobenzene | HCID 59386372 | — |
| Product | 2,3-difluoro-N-(2-fluoro-4-iodophenyl)-5-(2-methoxyethoxy)-6-nitroaniline | HCID 59386301 | 32% |
Reaction Steps
2-Fluoro-4-iodoaniline (1.6 g, 6.8 mmol) and 1,2,3-trifluoro-5-(2-methoxyethoxy)-4-nitrobenzene (1.7 g, 6.8 mmol) were reacted using the condition described in Example 1 (Step A) to form the title compound (1.02 g, 32%); m/z=467 [M−1].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08648116B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-53f7da8dc5a248e78e8266a2b2581c24 |
| Source note | uspto-grants-2014_02 |