HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloroaniline → 2-Bromo-5-[(4-chloro-phenyl)-(3-chloro-phenylamino)-methyl]-1-isopropyl-1H-imidazole-4-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloroaniline | HCID 7932 | — |
| Reactant | ethyl 2-bromo-5-((4-chlorophenyl)(hydroxy)methyl)-1-isopropyl-1H-imidazole-4-carboxylate | HCID 86707749 | — |
| Product | 2-Bromo-5-[(4-chloro-phenyl)-(3-chloro-phenylamino)-methyl]-1-isopropyl-1H-imidazole-4-carboxylic acid ethyl ester | HCID 86707766 | — |
Reaction Steps
The title compound was prepared in analogy to the procedure described for step E2 using 2-bromo-5-[(4-chloro-phenyl)-hydroxy-methyl]-1-isopropyl-1H-imidazole-4-carboxylic acid ethyl ester (intermediate B) and 3-chloro-aniline as starting materials. tR: 1.45 min (LC-MS 2); ESI-MS: 510.1/512.1 [M+H]+ (LC-MS 2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08815926B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-34072c26684445e38089074585aa0e5b |
| Source note | uspto-grants-2014_08 |