Potassium Hydroxide → HCID 86692172, compound

Participants

Reaction Steps

To a solution of (E)-ethyl 8-tert-butyl-2-oxo-6-(3-oxo-3-p-tolylprop-1-enyl)-2H-chromene-3-carboxylate (0.5 g, 1.19 mmol) in ethanol (50 mL) was added 10% aqueous KOH (10 mL), and the mixture was vigorously stirred for 1 h at room temperature. After completion of the reaction, the solvents were removed and the residue was acidified with dilute hydrochloric acid (HCl) (2 N). The precipitate was separated by filtration and dried over vacuum. The residue was washed with methanol to give (E)-8-tert-butyl-2-oxo-6-(3-oxo-3-p-tolylprop-1-enyl)-2H-chromene-3-carboxylic acid of Formula V (0.31 g, 64% yield).

Provenance & Evidence