1,1,1-Trimethoxypropane → HCID 68777322, compound

HRID 241030Notes

Reaction equation

HRID 241030 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([NH2:9])[C:5]([NH2:8])=[N:6][CH:7]=1.[C:10](OC)(OC)(OC)[CH2:11][CH3:12].[CH3:19][Si:20]([CH3:27])([CH3:26])[CH2:21][CH2:22][O:23][CH2:24]Cl>>[Br:1][C:2]1[CH:3]=[C:4]2[N:9]=[C:10]([CH2:11][CH3:12])[N:8]([CH2:24][O:23][CH2:22][CH2:21][Si:20]([CH3:27])([CH3:26])[CH3:19])[C:5]2=[N:6][CH:7]=1

Participants

4

Reactant 3

HCID 1411451,1,1-TrimethoxypropaneHCID 6911565-Bromopyridine-2,3-diamineHCID 27242712-Chloromethyl 2-(trimethylsilyl)ethyl ether

Product 1

HCID 68777322HCID 68777322, compound

Procedure

Synthesized according to the method of reagent preparation 19 by using 5-bromo-2,3-diaminopyridine and trimethyl orthopropionate in step 2 and 2-(trimethylsilyl)ethoxymethyl chloride in step 3. MS (EI) for C14H22BrN3OSi: 357 (MH+).

Workup

  1. customSynthesized
  2. customaccording to the method of reagent preparation 19

Sources & evidence

ORD record
ord-b5917a41d9c44be0ad7472b09b7419c9
Source dataset
uspto-grants-2014_02
Patent number
US08648066B2

Reaction notes

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