HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Piperidinemethanol → Methyl 1-{[4-(hydroxymethyl)piperidin-1-yl]methyl}cyclopentanecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Piperidinemethanol | HCID 420771 | — |
| Reactant | Methyl 1-formylcyclopentanecarboxylate | HCID 10931680 | — |
| Reactant | Methyl 1-formylcyclobutane-1-carboxylate | HCID 15656335 | — |
| Product | Methyl 1-{[4-(hydroxymethyl)piperidin-1-yl]methyl}cyclopentanecarboxylate | HCID 69317059 | — |
Reaction Steps
The title compound was prepared according to the procedure described in Step 3 of EXAMPLE 2 using piperidin-4-ylmethanol and methyl 1-formylcyclopentanecarboxylate (Synthesis, 1997, 32) instead of 3-(piperidin-4-ylmethoxy)-4-(2,2,2-trifluoroethoxy)-1,2-benzisoxazole and methyl 1-formylcyclobutanecarboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816090B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-1a8ac5c1e38844cfb245f0c5e262d58c |
| Source note | uspto-grants-2014_08 |