Methyl 1-formylcyclopentanecarboxylate → Methyl 4-[2-(4-{[(4-isobutoxy-1,2-benzisoxazol-3-yl)oxy]methyl}piperidin-1-yl)ethyl]tetrahydro-2H-pyran-4-carboxylate

Participants

Reaction Steps

The title compound was prepared according to the procedure described in Step 3 of EXAMPLE 2 using 4-isobutoxy-3-(piperidin-4-ylmethoxy)-1,2-benzisoxazole (EXAMPLE 10, Step 1) and methyl 4-(2-oxoethyl)tetrahydro-2H-pyran-4-carboxylate (WO 2004/043958) instead of 3-(piperidin-4-ylmethoxy)-4-(2,2,2-trifluoroethoxy)-1,2-benzisoxazole and methyl 1-formylcyclopentanecarboxylate.

Provenance & Evidence