Methyl 1-formylcyclopentanecarboxylate → HCID 178501100, compound

HRID 2410341Notes

Reaction equation

HRID 2410341 reaction equation
[CH2:1]([O:5][C:6]1[C:11]2[C:12]([O:15][CH2:16][CH:17]3[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]3)=[N:13][O:14][C:10]=2[CH:9]=[CH:8][CH:7]=1)[CH:2]([CH3:4])[CH3:3].[CH:23]([C@H:25]1[CH2:30][CH2:29][C@H:28]([C:31]([O:33][CH3:34])=[O:32])[CH2:27][CH2:26]1)=O.C(C1(C(OC)=O)CCCC1)=O>>[CH2:1]([O:5][C:6]1[C:11]2[C:12]([O:15][CH2:16][CH:17]3[CH2:22][CH2:21][N:20]([CH2:23][C@H:25]4[CH2:26][CH2:27][C@H:28]([C:31]([O:33][CH3:34])=[O:32])[CH2:29][CH2:30]4)[CH2:19][CH2:18]3)=[N:13][O:14][C:10]=2[CH:9]=[CH:8][CH:7]=1)[CH:2]([CH3:4])[CH3:3]

Participants

4

Reactant 3

HCID 10931680Methyl 1-formylcyclopentanecarboxylateHCID 693169774-Isobutoxy-3-(piperidin-4-ylmethoxy)-1,2-benzisoxazoleHCID 178501146HCID 178501146, compound

Product 1

HCID 178501100HCID 178501100, compound

Procedure

The title compound was prepared according to the procedure described in Step 3 of EXAMPLE 2 using 4-isobutoxy-3-(piperidin-4-ylmethoxy)-1,2-benzisoxazole (EXAMPLE 10, Step 1) and methyl trans-4-formylcyclohexanecarboxylate (JP 49048639) instead of 3-(piperidin-4-ylmethoxy)-4-(2,2,2-trifluoroethoxy)-1,2-benzisoxazole and methyl 1-formylcyclopentanecarboxylate.

Sources & evidence

ORD record
ord-42eff46445fc43cf96d405c023d4636c
Source dataset
uspto-grants-2014_08
Patent number
US08816090B2

Reaction notes

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