HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopentanemethanol → tert-Butyl 4-({[4-(cyclopentylmethoxy)-1,2-benzisoxazol-3-yl]oxy}methyl)piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopentanemethanol | HCID 77195 | — |
| Reactant | Methyl 1-{[4-(hydroxymethyl)piperidin-1-yl]methyl}cyclopentanecarboxylate | HCID 69317059 | — |
| Reactant | HCID 136263840 | HCID 136263840 | — |
| Product | tert-Butyl 4-({[4-(cyclopentylmethoxy)-1,2-benzisoxazol-3-yl]oxy}methyl)piperidine-1-carboxylate | HCID 69317710 | — |
Reaction Steps
The title compound was prepared according to the procedure described in Step 4 of EXAMPLE 9 using tert-butyl 4-{[(4-hydroxy-1,2-benzisoxazol-3-yl)oxy]methyl}piperidine-1-carboxylate (EXAMPLE 17, Step 2) and cyclopentylmethanol instead of 4-[(4-methoxybenzyl)oxy]-1,2-benzisoxazol-3-ol and methyl 1-{[4-(hydroxymethyl)piperidin-1-yl]methyl}cyclopentanecarboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816090B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-86a35938e8ad48fa9f005cdb6e27051e |
| Source note | uspto-grants-2014_08 |