2-Chloro-6-methylbenzene-1-sulfonyl chloride → HCID 86628002, compound

HRID 241046Notes

Reaction equation

HRID 241046 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([NH2:9])[C:5]([Cl:8])=[N:6][CH:7]=1.[Cl:10][C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([CH3:17])[C:12]=1[S:18](Cl)(=[O:20])=[O:19]>>[Br:1][C:2]1[CH:3]=[C:4]([NH:9][S:18]([C:12]2[C:13]([CH3:17])=[CH:14][CH:15]=[CH:16][C:11]=2[Cl:10])(=[O:19])=[O:20])[C:5]([Cl:8])=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 157253702-Chloro-6-methylbenzene-1-sulfonyl chlorideHCID 218583543-Amino-5-bromo-2-chloropyridine

Product 1

HCID 86628002HCID 86628002, compound

Procedure

Prepared according to the methods described in reagent preparation 26 using 5-bromo-2-chloropyridin-3-amine and 2-chloro-6-methylbenzene-1-sulfonyl chloride in step 1. MS (EI) for C12H9BrCl2N2O2S: 393, 395, 397 (Br+Cl isotopes, MH+).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-e6b42de0548a424f8ac4b70ce9fd55ec
Source dataset
uspto-grants-2014_02
Patent number
US08648066B2

Reaction notes

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