Acetyl chloride → N-(5-Bromo-2-chloro-3-pyridinyl)acetamide

HRID 241047Notes

Reaction equation

HRID 241047 reaction equation

[Br:1][C:2]1[CH:3]=[C:4]([NH2:9])[C:5]([Cl:8])=[N:6][CH:7]=1.[C:10](Cl)(=[O:12])[CH3:11]>>[Br:1][C:2]1[CH:3]=[C:4]([NH:9][C:10](=[O:12])[CH3:11])[C:5]([Cl:8])=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 6367Acetyl chloride

HCID 218583543-Amino-5-bromo-2-chloropyridine

Product 1

HCID 59620063N-(5-Bromo-2-chloro-3-pyridinyl)acetamide

Procedure

Prepared according to the methods described in reagent preparation 26 using 5-bromo-2-chloropyridin-3-amine and acetyl chloride in step 1.

Workup

customPrepared

Sources & evidence

ORD record: ord-fd0699531a514e6a801f10610719b6ab
Source dataset: uspto-grants-2014_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08648066B2

Reaction notes

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