Sarcosine t-butyl ester hydrochloride → HCID 66678670, compound

HRID 2410529Notes

Reaction equation

HRID 2410529 reaction equation
Br[CH2:2][C:3]1[CH:4]=[C:5]([CH:8]=[C:9]([Cl:11])[CH:10]=1)[C:6]#[N:7].Cl.[C:13]([O:17][C:18](=[O:22])[CH2:19][NH:20][CH3:21])([CH3:16])([CH3:15])[CH3:14]>>[Cl:11][C:9]1[CH:10]=[C:3]([CH:4]=[C:5]([C:6]#[N:7])[CH:8]=1)[CH2:2][N:20]([CH3:21])[CH2:19][C:18]([O:17][C:13]([CH3:16])([CH3:15])[CH3:14])=[O:22]

Participants

3

Reactant 2

HCID 11252350Sarcosine t-butyl ester hydrochlorideHCID 583696103-(Bromomethyl)-5-chlorobenzonitrile

Product 1

HCID 66678670HCID 66678670, compound

Procedure

The title compound was prepared following general procedure 10, starting from 3-(bromomethyl)-5-chlorobenzonitrile and sarcosine tert-butyl ester hydrochloride. It was isolated as a yellow oil (570 mg, 78%). LC/MS (Method B): 295.1 (M+H)+.

Sources & evidence

ORD record
ord-a0064c3fe0604199af76e6d828a52d92
Source dataset
uspto-grants-2014_08
Patent number
US08815919B2

Reaction notes

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