Isopropylamine → Benzonitrile, 3-(((1-methylethyl)amino)methyl)-

HRID 2410543Notes

Reaction equation

Br[CH2:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[C:6]#[N:7].[CH:11]([NH2:14])([CH3:13])[CH3:12]>>[CH:11]([NH:14][CH2:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[C:6]#[N:7])([CH3:13])[CH3:12]

Participants

Reactant 2

HCID 6363Isopropylamine

HCID 97249Benzonitrile, 3-(bromomethyl)-

Product 1

HCID 485406Benzonitrile, 3-(((1-methylethyl)amino)methyl)-

Procedure

The title compound was prepared following general procedure 10, starting from 3-(bromomethyl)benzonitrile and isopropyl amine. It was isolated as a yellow liquid (5.7 g, 92%).

Sources & evidence

ORD record: ord-a1e142b50fb24ac39f41afcf5412968f
Source dataset: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08815919B2

Reaction notes

Loading…