Tert-butyl[{3-[amino(hydroxyimino)methyl]benzyl}(methyl)amino]acetate → Tert-butyl N-(3-{5-[4-(2-ethylpiperidin-1-yl)-3-(methoxymethyl)phenyl]-1,2,4-oxadiazol-3-yl}benzyl)-N-methylglycinate

Participants

Reaction Steps

Tert-butyl N-(3-{5-[4-(2-ethylpiperidin-1-yl)-3-(methoxymethyl)phenyl]-1,2,4-oxadiazol-3-yl}benzyl)-N-methylglycinate was prepared following the general procedure 3 starting from Intermediate 9 and Intermediate 21. It was hydrolyzed following general procedure 8 to afford the title compound as a white powder. LC/MS (Method B): 479.4 (M+H)+, 477.4 (M−H)−. HPLC (Method A) Rt 2.74 min (Purity: 98.5%).

Provenance & Evidence