2-(Methoxymethyl)-2'-methylbiphenyl-4-carboxylic acid → HCID 58066314, compound

HRID 2410577Notes

Reaction equation

HRID 2410577 reaction equation
[CH3:1][O:2][CH2:3][C:4]1[CH:9]=[C:8]([C:10]([OH:12])=O)[CH:7]=[CH:6][C:5]=1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[CH3:19].O[N:21]=[C:22]([C:24]1[CH:29]=[CH:28][C:27]([O:30][CH2:31][CH2:32][OH:33])=[CH:26][CH:25]=1)[NH2:23]>>[CH3:1][O:2][CH2:3][C:4]1[CH:9]=[C:8]([C:10]2[O:12][N:23]=[C:22]([C:24]3[CH:29]=[CH:28][C:27]([O:30][CH2:31][CH2:32][OH:33])=[CH:26][CH:25]=3)[N:21]=2)[CH:7]=[CH:6][C:5]=1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[CH3:19]

Participants

3

Reactant 2

HCID 594958222-(Methoxymethyl)-2'-methylbiphenyl-4-carboxylic acidHCID 74866742HCID 74866742, compound

Product 1

HCID 58066314HCID 58066314, compound

Procedure

The title compound was prepared following the general procedure 4 starting from Intermediate 3 and Intermediate 27 affording the product as colorless oil. LC/MS (Method B): 417.3 (M+H)+. HPLC (Method A) Rt 5.43 min (Purity: 96.4%).

Sources & evidence

ORD record
ord-e5ed0d4b33d74c5688001538080a4295
Source dataset
uspto-grants-2014_08
Patent number
US08815919B2

Reaction notes

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