HuagongsheHuagongshe Chemistry Print Report · For research reference only
Vanillylmandelic Acid → N-heptyl-2-hydroxy-2-(4-hydroxy-3-methoxyphenyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Vanillylmandelic Acid | HCID 1245 | — |
| Reactant | 1-Heptanamine | HCID 8127 | — |
| Reactant | N-(heptan-4-yl)-2-hydroxy-2-(4-hydroxy-3-methoxyphenyl)acetamide | HCID 49854208 | — |
| Product | N-heptyl-2-hydroxy-2-(4-hydroxy-3-methoxyphenyl)acetamide | HCID 12106248 | 89% |
Reaction Steps
N-heptyl-2-hydroxy-2-(4-hydroxy-3-methoxyphenyl)acetamide was prepared from 4-hydroxy-3-methoxymandelic acid and n-heptylamine by the same procedure described for the preparation of N-(heptan-4-yl)-2-hydroxy-2-(4-hydroxy-3-methoxyphenyl)acetamide. White crystals of the title compound (6.7 g, 89% yield) were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816102B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-2fb8963808e944b38a86ad8da0970f8c |
| Source note | uspto-grants-2014_08 |