HCID 66604924, compound → HCID 178497266, compound

Participants

Reaction Steps

An solution of methyl 7-(benzyloxy)-2-(4-chlorophenyl)-5H-pyrido[3,2-b]indole-4-carboxylate (709 mg, 1.60 mmol) in trifluoroacetic acid (15 mL) was heated at 70° C. for 30 min. The solvent was removed and the residue was suspended in a mixture of EtOAc (25 mL) and hexane (50 mL). The suspended solid was collected by filtration and washed with the EtOAc/hexane mixture. This gave impure methyl 2-(4-chlorophenyl)-7-hydroxy-5H-pyrido[3,2-b]indole-4-carboxylate (573 mg). MS (ESI) m/z 353.0 (M+H).

Provenance & Evidence