2-(Dimethylamino)ethanol → HCID 66605399, compound

HRID 2410774Notes

Reaction equation

HRID 2410774 reaction equation
[OH:1][C:2]1[CH:3]=[CH:4][C:5]2[C:6]3[N:14]=[C:13]([C:15]4[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=4)[CH:12]=[C:11]([C:21]([NH2:23])=[O:22])[C:7]=3[NH:8][C:9]=2[CH:10]=1.[CH3:24][N:25]([CH3:29])[CH2:26][CH2:27]O>>[CH3:24][N:25]([CH3:29])[CH2:26][CH2:27][O:1][C:2]1[CH:3]=[CH:4][C:5]2[C:6]3[N:14]=[C:13]([C:15]4[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=4)[CH:12]=[C:11]([C:21]([NH2:23])=[O:22])[C:7]=3[NH:8][C:9]=2[CH:10]=1

Participants

3

Reactant 2

HCID 79022-(Dimethylamino)ethanolHCID 178513536HCID 178513536, compound

Product 1

HCID 66605399HCID 66605399, compound

Procedure

This was similarly prepared from 7-hydroxy-2-phenyl-5H-pyrido[3,2-b]indole-4-carboxamide and 2-(dimethylamino)ethanol. MS (ESI) m/z 375.1 (M+H). 1H NMR (500 MHz, MeOD) δ ppm 8.25-8.33 (1H, m), 8.16 (1H, s), 8.08-8.13 (2H, m), 7.53 (2H, t, J=7.78 Hz), 7.44 (1H, t, J=7.32 Hz), 7.20 (1H, d, J=2.14 Hz), 6.98 (1H, dd, J=8.85, 2.14 Hz), 4.30 (2H, t, J=5.34 Hz), 3.01 (2H, t, J=5.34 Hz), 2.52 (6H, s).

Sources & evidence

ORD record
ord-349ba66a90c745589b75d06aba35071a
Source dataset
uspto-grants-2014_08
Patent number
US08815840B2

Reaction notes

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