Hydrochloric Acid → HCID 66604430, compound

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Reaction Steps

This was similarly prepared from 7-hydroxy-2-phenyl-5H-pyrido[3,2-b]indole-4-carboxamide and tert-butyl 2-hydroxyethyl(methyl)carbamate except that the crude product was deprotected with a mixture of MeOH (1 mL) and conc. HCl (1 mL) before purification. MS (ESI) m/z 361.12 (M+H). 1H NMR (500 MHz, MeOD) δ ppm 8.29 (1H, d, J=8.85 Hz), 8.16 (1H, s), 8.11 (2H, d, J=7.02 Hz), 7.54 (2H, t, J=7.78 Hz), 7.44 (1H, t, J=7.32 Hz), 7.21 (1H, d, J=2.14 Hz), 6.98 (1H, dd, J=8.70, 2.29 Hz), 4.25 (2H, t, J=5.19 Hz), 3.05 (2H, t, J=5.19 Hz), 2.51 (3H, s).

Provenance & Evidence