Tert-butyl 4-hydroxypiperidine-1-carboxylate → HCID 66605107, compound

Participants

Reaction Steps

This was similarly prepared from 7-hydroxy-2-phenyl-5H-pyrido[3,2-b]indole-4-carboxamide and tert-butyl 4-hydroxypiperidine-1-carboxylate. MS (ESI) m/z 387.1 (M+H). 1H NMR (500 MHz, DMSO-d6) δ ppm 11.35 (1H, br. s.), 8.57 (1H, s), 8.36 (1H, s), 8.28 (2H, d, J=7.02 Hz), 8.12 (1H, d, J=8.55 Hz), 7.84 (1H, s), 7.54 (2H, t, J=7.63 Hz), 7.42 (1H, t, J=7.32 Hz), 7.32 (1H, d, J=2.14 Hz), 6.91 (1H, dd, J=8.85, 2.14 Hz), 4.43-4.57 (1H, m), 3.05 (2H, ddd, J=12.67, 4.27, 4.12 Hz), 2.61-2.74 (2H, m), 1.98-2.11 (2H, m), 1.91 (3H, s), 1.50-1.68 (2H, m).

Provenance & Evidence