Aniline → 6-chloro-5-methyl-N-phenylpyrimidin-4-amine

HRID 241082Notes

Reaction equation

HRID 241082 reaction equation
[Cl:1][C:2]1[N:7]=[CH:6][N:5]=[C:4](O)[C:3]=1[CH3:9].[NH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[Cl:1][C:2]1[N:7]=[CH:6][N:5]=[C:4]([NH:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:3]=1[CH3:9]

Participants

3

Reactant 2

HCID 6115AnilineHCID 178431783HCID 178431783, compound

Product 1

HCID 637349086-chloro-5-methyl-N-phenylpyrimidin-4-amine

Procedure

Synthesized according to the method of reagent preparation 49 using 6-chloro-5-methylpyrimidin-4-ol and aniline in step 1.

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-efc45c9d45454e0db5bcd5c1d69a2d8c
Source dataset
uspto-grants-2014_02
Patent number
US08648066B2

Reaction notes

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