1-tert-Butyl-4-piperidone → HCID 66604878, compound

Participants

Reaction Steps

This was similarly prepared from 7-amino-2-(3-(trifluoromethyl)phenyl)-5H-pyrido[3,2-b]indole-4-carboxamide and 1-(t-butyl)piperidin-4-one. MS (ESI) m/z 510.35 (M+H). 1H NMR (500 MHz, DMSO-d6) δ ppm 11.10 (1H, s), 8.55-8.63 (2H, m), 8.51 (1H, br. s.), 8.30 (1H, s), 7.90 (1H, d, J=8.55 Hz), 7.80 (1H, br. s.), 7.70-7.78 (2H, m), 6.85 (1H, d, J=1.83 Hz), 6.63 (1H, dd, J=8.70, 1.98 Hz), 6.04 (1H, d, J=7.63 Hz), 3.23 (1H, dd, J=10.22, 3.81 Hz), 2.95-3.08 (2H, m), 2.21 (2H, t, J=10.99 Hz), 2.02 (2H, d, J=12.82 Hz), 1.34-1.52 (2H, m), 1.06 (9H, s).

Provenance & Evidence