Ammonia methanol → HCID 86663072, compound

Participants

Reaction Conditions

Reaction Steps

Methyl 2-bromo-8-(morpholine-4-carbonyl)-5H-pyrido[3,2-b]indole-4-carboxylate (220 mg, 0.526 mmol) was mixed with NH3/MeOH(7N) (18 mL, 126 mmol) in a sealed microwave vial. The mixture was heated at 105° C. for 2.5 hrs in microwave. The mixture was concentrated to give 205 mg crude product. MS (ESI) m/z 402.95 (M+H)+.

Provenance & Evidence