HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2410919Generated: November 2, 2026
Sodium Carbonate → 3-bromo-7-(pyridin-3-yl)-9H-carbazole-1-carboxamide
https://huagongshe.com/reaction/2410919
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 3-Pyridinylboronic acid | HCID 2734378 | — |
| Reactant | 3-bromo-7-iodo-9H-carbazole-1-carboxamide | HCID 66604592 | — |
| Catalyst | HCID 178418807 | HCID 178418807 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | 3-bromo-7-(pyridin-3-yl)-9H-carbazole-1-carboxamide | HCID 66605931 | — |
Reaction Steps
3-Bromo-7-iodo-9H-carbazole-1-carboxamide (100 mg, 0.241 mmol), pyridin-3-ylboronic acid (35.5 mg, 0.289 mmol), PdCl2(dppf)-CH2Cl2 adduct (39.4 mg, 0.048 mmol), and Na2CO3 (2M) (0.482 mL, 0.964 mmol) were mixed with DME (4 mL) in a sealed microwave vial. The mixture was flushed with N2 and heated at 105° C. in an oil bath for 5 hrs. The mixture was used as it is. MS (ESI) m/z 365.88 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08815840B2 |
|---|
| Source dataset | uspto-grants-2014_08 |
|---|
| ORD ID | ord-1bbefaf5eb84483ea4d08aab732849b8 |
|---|
| Source note | uspto-grants-2014_08 |
|---|
