HCID 66615383, compound → HCID 66615301, compound

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Reaction Steps

tert-Butyl 4-(8-carbamoyl-6-(3-methyl-4-(morpholinomethyl)phenyl)-9H-carbazol-2-yl)-5,6-dihydropyridine-1(2H)-carboxylate 484 (12 mg, 0.021 mmol) and palladium on carbon (20 mg, 0.019 mmol) were mixed with MeOH (10 ml) in a sealed microwave tube. The mixture was stirred at r.t. with H2 in a balloon overnight. The mixture was filtered and then purified using preparative HPLC (MeOH/H2O/TFA) to give titled product. MS (ESI) m/z 583.19 (M+H)+.

Provenance & Evidence