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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2410947Generated: November 1, 2026

2-(2-(Cyclopropylmethoxy)-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane → ethyl 7-[2-(cyclopropylmethoxy)-4-fluorophenyl]-2-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxylate

https://huagongshe.com/reaction/2410947

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(2-(Cyclopropylmethoxy)-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneHCID 56923640—
Reactantethyl-7-chloro-2-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxylateHCID 67774803—
Productethyl 7-[2-(cyclopropylmethoxy)-4-fluorophenyl]-2-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxylateHCID 67775352—

Reaction Steps

Starting from ethyl-7-chloro-2-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxylate (example A3) and 2-(2-cyclopropylmethoxy-4-fluoro-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane (example B.c3) the title compound is obtained as off-white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08816085B2
Source datasetuspto-grants-2014_08
ORD IDord-ab45d2e05fde45b3b6b297987afc8ce4
Source noteuspto-grants-2014_08