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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2410948Generated: November 2, 2026

2-(2-(Cyclopropylmethoxy)-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane → ethyl 7-[2-(cyclopropylmethoxy)-5-fluorophenyl]-2-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxylate

https://huagongshe.com/reaction/2410948

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(2-(Cyclopropylmethoxy)-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneHCID 56923638—
Reactantethyl-7-chloro-2-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxylateHCID 67774803—
Productethyl 7-[2-(cyclopropylmethoxy)-5-fluorophenyl]-2-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxylateHCID 67773577—

Reaction Steps

Starting from ethyl-7-chloro-2-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxylate (example A3) and 2-(2-cyclopropylmethoxy-5-fluoro-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane (example B.c4) the title compound is obtained as off-white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08816085B2
Source datasetuspto-grants-2014_08
ORD IDord-041b08b60a7c4c8594e5be58dbca222e
Source noteuspto-grants-2014_08