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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2410952Generated: November 1, 2026

2-(2-Cyclopropylmethoxy-4-fluoro-5-methoxy-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane → ethyl 7-[2-(cyclopropylmethoxy)-4-fluoro-5-methoxyphenyl]-2-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxylate

https://huagongshe.com/reaction/2410952

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(2-Cyclopropylmethoxy-4-fluoro-5-methoxy-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolaneHCID 66866377—
Reactantethyl-7-chloro-2-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxylateHCID 67774803—
Productethyl 7-[2-(cyclopropylmethoxy)-4-fluoro-5-methoxyphenyl]-2-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxylateHCID 67774553—

Reaction Steps

Starting from ethyl-7-chloro-2-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxylate (example A3) and 2-(2-Cyclopropylmethoxy-4-fluoro-5-methoxy-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane (example B.c2) the title compound is obtained as off-white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08816085B2
Source datasetuspto-grants-2014_08
ORD IDord-bdcd8e86aa814032828fee3c69efe222
Source noteuspto-grants-2014_08