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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2410983Generated: November 2, 2026

(3R,4R)-3-Amino-1-Boc-4-hydroxypyrrolidine → HCID 86666013, compound

https://huagongshe.com/reaction/2410983

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3R,4R)-3-Amino-1-Boc-4-hydroxypyrrolidineHCID 11275699—
ReactantHCID 67772801HCID 67772801—
ProductHCID 86666013HCID 86666013—

Reaction Steps

Starting from 7-[2-(cyclopropylmethoxy)-4-fluoro-5-methoxyphenyl]-2-methyl-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[3,2-b]pyridine-3-carboxylic acid (example D.c7) and commercially available tert-butyl (3R*,4R*)-3-amino-4-hydroxy-pyrrolidine-1-carboxylate the title compound is obtained as pale yellow viscous oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08816085B2
Source datasetuspto-grants-2014_08
ORD IDord-8482f71b4050474dad53e740049c1f10
Source noteuspto-grants-2014_08