HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methoxyacetyl chloride → 7-[2-(Cyclopropylmethoxy)-4-methoxyphenyl]-N-[1-(methoxyacetyl)piperidin-4-yl]-2-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methoxyacetyl chloride | HCID 96623 | — |
| Reactant | HCID 67773953 | HCID 67773953 | — |
| Product | 7-[2-(Cyclopropylmethoxy)-4-methoxyphenyl]-N-[1-(methoxyacetyl)piperidin-4-yl]-2-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxamide | HCID 67775231 | — |
Reaction Steps
Starting from 7-[2-(cyclopropylmethoxy)-4-methoxyphenyl]-2-methyl-N-(piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridine-3-carboxamide hydrochloride (example D.f11) and commercially methoxy-acetyl chloride the title compound is obtained as colorless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816085B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-4ce6687e84dd434fbd93e7cb9c334b08 |
| Source note | uspto-grants-2014_08 |